Saturday , March 6 2021

Health | The appendix would play a role in the beginning of Parkinson's disease



What happens if Parkinson's disease did not develop only in the brain? A disease called neurodegenerative can be one of its origins in the digestive system. A study of 1.5 million people in Sweden, published in the journal Science Translational Medicine, found a connection between the removal of appendicit and the appearance of Parkinson's disease.

Performed on 1.7 million people, the study found that people who had removed the attachment were up to 20% less likely to develop Parkinson's disease. On the other hand, people who have had appendectomy and have had a delayed onset of the disease with 4 years on average.

In addition, lumps of proteins previously associated with the disease have been discovered in the addition and in other parts of the digestive system, thus adding the existing evidence that connects the intestines to the brain's disease.

The attachment is not useful

The annex contains a protein, alpha synuclein, which is known to accumulate in the brain in patients with Parkinson's disease. "Alpha synuclein is a protein that does not like to remain immobile, it can move from neuron to neuron, if it enters the brain, it can coagulate and spread and have neurotoxic effects that can lead to Parkinson's disease", describes Viviane Labrie, one of the authors of the study.

Although its reputation is largely unnecessary, the Annex plays an important role in our immune system, to regulate the composition of our intestinal bacteria and now, as this study shows, in the appearance of Parkinson's disease.

Be careful, but this study does not recommend removing the attachment far from it. "We do not say that if you had ablation, you will not have Parkinson's disease"warns the researcher. Currently, no cause-and-effect relationship has been established. As with studies of this type, other factors that can not be explained explain the difference between those ablated and others.


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