MADRID, Feb. 11 (EUROPE PRESS) –
The exercise exercise provides a hormone that can improve memory and protect against Alzheimer's, as evidenced by a study conducted by researchers from the Faculty of Physicians and Surgeons of the University of Columbia (USA) and it has been published in the magazine & # 39; Herbal & # 39 ;.
A few years ago, the researchers discovered a hormone called irisin, which was released to the circulation during physical activity. Initial studies suggested that irisin played an important role in the energy supply, although recent research found that the hormone can also promote neuronal growth in the brain hippocampus, a critical region for learning and memory.
"This raised the possibility that irisin can help explain why physical activity improves memory and seems to play a protective role in brain diseases such as Alzheimer's disease," the researchers said. researchers from Brazil and Canada.
Specifically in the experts, the experts sought a link between irisin and Alzheimer's in humans, and by means of brain tissue samples, they found that irisin is present in the human hippocampus and that the hormone's hippocampal levels are reduced in humans with Alzheimer's.
Study done in MICE
To investigate what makes iris in the brain, the team turned to mice and noted that irisin protected them from brain synapse and memory. Then they analyzed the effect of exercise on the iris and brain and discovered that mice that swam almost every day for five weeks did not develop memory problems despite having infusions of beta-amyloid, the protein that prevents neurons, and involved in Alzheimer's.
The researchers also found that blocking iris with a medication completely eliminated the benefits of swimming. In fact, mice that swam and were treated with irisin blocking agents did not perform better on memory tests than sedentary animals that had received beta amyloid infusions.
Before all this, experts have suggested that irisin could be utilized to find a new therapy for the prevention or treatment of dementia in humans, Arancio says. Therefore, they seek pharmaceutical compounds that can increase brain levels of the hormone or which can mimic its effect.
"Meanwhile, I would definitely encourage everyone to exercise, to promote brain function and health in general." But it is not possible for many people, especially those with age-related conditions such as heart disease, arthritis or dementia. . For these people, there is a particular need for drugs that can mimic the effects of iris and protect synapses and prevent cognitive decline, "they have decided.