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Wake up early reduces the risk of breast cancer, says the study



Researchers also claim that sleep more than those recommended eight hours a night can increase the risk of the disease

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7 Nov 2018, 19h12 – Published November 7, 2018, 18h06

Women who prefer to get up early risk up to 48% lower to develop breast cancer, according to a study presented in 2018 NCRI Cancer Conference, which took place this week in Scotland. The researchers also found that women who slept more than the recommended eight hours per night were more likely to get the condition, which increased by 20% every additional hour's sleep.

Already World Health Organization (WHO) has recently been warned that work at night can increase the likelihood of cancer in women.

For the researchers, the results of the new study are relevant since Sleep quality (or lack of it) interferes with various biological functions, including disease emergencies, such as depression. Therefore, the science community always researches the relationship between sleep and disease risks in general as a way to find out what types of behavioral modifications can help to reduce them.

The study

The researchers analyzed more than 385,000 women whose data were found in the project Biobank, a long-term study investigating the genetic and environmental causes of breast cancer. In addition, the team was given access to information on the genomic association of the disease obtained through the BCAC Breast Cancer Association.

In order to detect the connection between trends in sleep patterns and the risk of breast cancer, the study was used Mendel randomization, a method in which genetic variants are studied that can interfere with the onset of disease, such as breast cancer, and how these variants can affect properties of sleep.

Each participant underwent an analysis of 341 DNA fragments whose function is to control the inclination of being a day or night person. These fragments are defined at birth and therefore do not suffer from external changes such as cancer and obesity, which illuminates the depths biological clock and breast cancer found in the study.

results

The results from BCAC data showed that early morning participants had a 40% lower risk of breast cancer compared to women with nightly habits. The biobank analysis indicated an even higher value: 48%. During eight years of follow-up, the researchers noted that two out of 100 women who preferred the evening developed the disease. For women with daily habits, this number is lower: one in 100.

Sleep duration also affects the likelihood of breast cancer: each hour more than sleep over recommended (7 to 8 hours per night) increases the risk by 20%. "The results are potentially very important because sleep is universal and easily modified," says Rebecca Richmond at the University of Bristol in BBC.

Despite this, the researchers pointed out that the reason for this link could not yet be determined. However, the team intends to continue investigating to understand changes in Sleep patterns could reduce the risks. "We would like to investigate the mechanisms underlying these results because they estimated the calculations based on morning or evening preferences, not if people actually wake up sooner or later," said Rebecca. Medical news today.

It is important to remember that according to National Cancer Institute (Inca), Genetic and hereditary factors (family history of breast cancer), environmental and behavioral factors (obesity, sedentary lifestyle and overweight during menopause) and reproductive and hormonal history (without children or breastfeeding) are the most important risk factors for the disease.


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