Tuesday , April 20 2021

Intermittent fasting which is beneficial for weight loss and glycemic control

Intermittent fasting that is beneficial for weight loss: How is it that meals, regardless of caloric intake, can promote weight loss?

Dietary trends continue to emerge and are phased in and out over the years from Atkins, Paleo to ketogenic diets. These trendy diets seem to catch the attention of many people, including patients with diabetes. Clinicians are constantly advising patients with type 2 diabetes on the importance of a healthy lifestyle, which often requires significant weight loss. Obesity is highly correlated with type 2 diabetes; therefore, patients with type 2 diabetes are often overwhelmed not only with a diabetes diagnosis but with the task of weight loss. This is when patients are tempted to look for the latest fad diet for an easy fix. One of the latest trendy diet plans is periodic fasting. Intermittent fasting consists of several different styles, including the 16/8 method, where fasting takes place 16 hours a day, or 5: 2 intermittent fasting, where fasting takes place for two full days a week. Food is not allowed during fixed periods; only water, coffee, tea and other non-caloric drinks are allowed. Are intermittent fasting beneficial for patients with type 2 diabetes?

Many health benefits have been linked to intermittent fasting, including weight loss, reduction in blood sugar and insulin levels, significant reduction of human growth hormone, and loss of body fat. Some studies even suggest that intermittent fasting can reduce the risk of heart disease, Alzheimer's disease and cancer. With the known effects on body weight, blood sugar and insulin levels, there is great interest in whether intermittent fasting can help prevent or treat diabetes.

A recent study examined the effects of different schedules of intermittent fasting on appetite, metabolism and fat burning. A small cohort of 11 adult men and women with obesity or obesity (BMI 25 – 35 mg / m)2) practiced two different meal time strategies in random order: a three-meal control plan over a 12-hour breakfast period. 8am and noon to noon. And an Early Timed Feeding (eTRF) plan with three meals over a six hour breakfast period. 8am and noon to noon. 14.00. Each schedule contained the same amount and type of food as the other. On the fourth day of each diet, the researchers measured the metabolism of participants in an airway chamber that measures calories, carbohydrates, fat, and protein burned. Participants ’appetite levels were screened every 3 hours while awake, and their hunger hormone level, ghrelin. The results showed that the eTRF plan decreased levels of hunger hormone, ghrelin; reduced appetite; and increased fat burning. This study had a significantly low population size but provides some objective measurements of the metabolic effects of intermittent fasting.

Previous studies were in conflict with whether intermittent fasting weight loss was attributed to burning more calories or reducing appetite. With the evidence from this recent study, it seems that the effect is not on the amount of calories burned, but more on the increased overall efficiency of metabolism. By limiting the time period to eat, the amount of calories consumed periodically will decrease in most people. It is also evident that there is a marked decrease in appetite while practicing periodic fasting. An observational study investigated the effect of intermittent fasting for 24 hours for 2-3 days per week on diabetes. Three men with overweight, hypertension and hyperlipidemia were able to lose 10-18% of their body weight, reduce their fasting blood sugar and HbA1c, and discontinue most, if not all, diabetes remedies. Although this study was only observational with only 3 patients, hearing about patients eliminating diabetes medication from their treatment plan is very significant.

While diabetic patients are searching for a cure for obesity to maintain glycemic control, intermittent fasting may be a topic of discussion to be addressed. It is important to discuss the risk of hypoglycaemia during fasting periods. While educating patients for proper carbohydrate counting, intake of important nutrients, and proper exercise, intermittent fasting may be a good recommendation for patients with diabetes.

Practice pearls:

  • Intermittent fasting is a diet that involves limiting caloric intake for periods such as 16/24 hours daily or for several days a week.
  • It has been found that intermittent fasting reduces appetite and hunger hormone and increases fat burning to induce weight loss, which can be effective for patients with diabetes and obesity.
  • Further research needs to be conducted to determine the causal relationship between intermittent fasting and glycemic control.

In this special interview, Dr. Mark Mattson, what resources are available to explain the intermittent diet and how to get started. Dr. Mark Mattson is the head of the Neuroscience Laboratory at the National Institute for Aging Intramural Research Program at NIH. He is also a professor of neuroscience at Johns Hopkins University. Part 1

References to "Intermittent fasting beneficial for weight loss and glycemic control":

"Mealtime strategies seem to lower appetite and improve fat burning. ”MDLinx, www.mdlinx.com/family-medicine/top-medical-news/article/2019/07/24/7573512?uic=ZZCE628C21DABE45DF95C1A9308F554865&utm_support_support Less Morning July25 & utm_term = Daily Update of Minor Specials with Daily Update

“Scheduled intermittent fasting can help reverse diabetes type 2, doctors suggest.” BMJ, www.bmj.com/company/newsroom/planned-intermittent-fasting-may-help-reverse-type-2-diabetes-suggest-doctors /.

Amber Satz, PharmD graduate, LECOM School of Pharmacy

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